Lead, Innate Immunity Cancer Cell Death Biology

Lead, Innate Immunity Cancer Cell Death Biology

About Astellas

Astellas is a global life sciences company committed to turning innovative science into VALUE for patients. We provide transformative therapies in disease areas that include oncology, ophthalmology, urology, immunology and women's health. Through our research and development programs, we are pioneering new healthcare solutions for diseases with high unmet medical need.

Learn more at Astellas.com.

Are you driven to make a real difference in the lives of patients?

We're seeking passionate individuals who thrive in dynamic environments, embrace new ideas, and aren't afraid to take intelligent risks. People who act with unwavering integrity and are deeply committed to making a tangible impact.

Purpose & Scope

This position supports antibody-drug conjugate (ADC) research in oncology by contributing to multiple discovery programs while managing and developing a team of scientists. Reporting to the Head of Innate Immunity & Cancer Cell Death Biology, the People Manager will balance project support with people management to enhance the quality and efficiency of ADC research.

The role also serves as a key support to the Head by providing practical scientific and operational input into research direction and new project opportunities.

Role and Responsibilities

Scientific Contribution

• Provide scientific input and review for multiple ADC discovery projects from pharmacology and biology perspectives
• Collaborate with project leads to support study design, data interpretation, and decision-making
• Apply prior experience in ADC and antibody research to improve overall project quality and execution
• Contribute to new project ideation by assessing feasibility and scientific rationale

People Management

• Line-manage scientists, including day-to-day supervision, coaching, and performance management
• Support team members' development and optimize role assignments based on strengths
• Foster a collaborative and open team environment to enhance communication and productivity

Operational Support

• Support the Head of Innate Immunity & Cancer Cell Death Biology in research and team operations
• Ensure appropriate communication of project progress and challenges to facilitate decision-making
• Promote effective collaboration with cross-functional partners (e.g., chemistry, biologics, DMPK)

Required Qualifications

• PhD, MD, or equivalent degree in pharmacology, oncology, immunology, or related life science field
• Approximately 8+ years of experience in pharmaceutical or biotech drug discovery
• Hands-on experience in antibody and ADC research
• Experience leading antibody and/or ADC projects as a project leader
• Prior people management or team leadership experience
• Solid understanding of pharmacology, including in vitro and in vivo evaluation and mechanism of action
• Experience working in cross-functional teams

Preferred Qualifications

• Player-coach mindset with the ability to contribute scientifically while managing a team
• Strong collaborative and problem-solving skills
• Proactive, flexible, and able to work effectively in a dynamic environment
• High integrity and strong sense of accountability
• Author of over 8 peer-reviewed publications in biology

Location and Working Environment

• This position is based in South San Francisco and will require on-site work/management in principle.
• Participation in meetings scheduled for early mornings and late nights is regularly required.

What awaits you at Astellas?

• Global collaboration: Become part of a connected global business of like-minded life science leaders, all dedicated to improving patients' lives worldwide.
• Real-world patient impact: Contribute to transformative therapies that reach patients around the world, knowing your work makes a difference every day.
• Relentless Innovation: Join a company at the forefront of scientific breakthroughs, where you'll have the opportunity to shape the future of healthcare.
• A Culture of Growth: Chart your own course within a supportive environment that values your contributions, champions your development, and empowers you to pursue your passions.

Our Organizational Values and Behaviors

Values: Innovation, Integrity and Impact sit at the heart of what we do.

Behaviors: We come together as 'One Astellas', working with courage and a sense of urgency. We are outcome focused and consistently take accountability for our personal contribution.

Salary Range

$145,460-$207,800 (Final compensation will be determined based on a variety of factors, including but not limited to skills, experience and organizational equity considerations)

Benefits:

• Medical, Dental and Vision Insurance
• Generous Paid Time Off options, including Vacation and Sick time, plus national holidays including year-end shut down
• 401(k) match and annual company contribution
• Company paid life insurance
• Annual Corporate Bonus and Quarterly Sales Incentive for eligible positions
• Long Term Incentive Plan for eligible positions
• Company fleet vehicle for eligible positions
• Referral bonus program

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